Research Chemicals Legal Highs Drug Infomation online Forum
  • Drug infomation
  • Buy Legal Highs UK
  • Buy Research Chemicals
  • Buy Legal Highs
  • Drug Forums
  • Helpfull Links
    • Drug Laws
  • Drugs Blog
  • Drug Legal Highs Research Chemical Videos
  • SEO Services
  • Contact

ResearchChemical 5IAI

4/18/2011

0 Comments

 
5-IAI From Wikipedia, the free encyclopedia Jump to: navigation, search 5-IAI Systematic (IUPAC) name 5-iodo-2,3-dihydro-1H-inden-2-amine Identifiers CAS number 132367-76-1 ATC code None PubChem CID 131506 ChemSpider 116224 Y Chemical data Formula C9H10IN  Mol. mass 259.087 g/mol SMILES eMolecules & PubChem InChI[show]
  • InChI=1S/C9H10IN/c10-8-2-1-6-4-9(11)5-7(6)3-8/h1-3,9H,4-5,11H2 Y
    Key: BIHPYCDDPGNWQO-UHFFFAOYSA-N Y
Therapeutic considerations Pregnancy cat.  ? Legal status Uncontrolled Routes Oral, Insufflated, Rectal  Y(what is this?)  (verify)
5-Iodo-2-aminoindane (5-IAI) is a drug which acts as a releasing agent of serotonin, norepinephrine, and dopamine.[1] It was developed in the 1990s by a team led by David E. Nichols at Purdue University.[2] 5-IAI fully substitutes for MDMA in rodents and is a putative entactogen in humans.[2] Unlike related aminoindane derivatives like MDAI and MMAI, 5-IAI causes some serotonergic neurotoxicity in rats, but is substantially less toxic than the its corresponding amphetamine homologue pIA, with the damage observed barely reaching statistical significance.[1]

[edit] See also
  • 2-Aminoindane (2-AI)
  • para-Iodoamphetamine (pIA)
  • 6-Chloro-2-aminotetralin (6-CAT)
[edit] References
  1. ^ a b Johnson MP, Conarty PF, Nichols DE (July 1991). "[3H]monoamine releasing and uptake inhibition properties of 3,4-methylenedioxymethamphetamine and p-chloroamphetamine analogues". European Journal of Pharmacology 200 (1): 9–16. PMID 1685125. 
  2. ^ a b Nichols DE, Johnson MP, Oberlender R (January 1991). "5-Iodo-2-aminoindan, a nonneurotoxic analogue of p-iodoamphetamine". Pharmacology, Biochemistry, and Behavior 38 (1): 135–9. PMID 1826785. http://linkinghub.elsevier.com/retrieve/pii/0091-3057(91)90601-W.
0 Comments



Leave a Reply.

    Advertise here for  £150 a Year
    Picture
    Picture
    Picture
    Picture

    Archives

    April 2020
    May 2015
    March 2015
    February 2015
    September 2011
    June 2011
    April 2011
    November 2010
    October 2010
    September 2010

    Categories

    All
    5iai
    5-iai
    Addiction
    Benso
    Benzo
    Chemical
    Chemicals
    Chems
    Design
    Drug
    Drugs
    Effects
    Herbal
    High
    Highs
    Information
    Ketammine
    Kratom
    Methoxdine
    Methoxetamine
    Mxe
    Nrg2
    Nrg3
    Powder
    Research
    Supply

    RSS Feed

    View my profile on LinkedIn

Research Chemical Suppliers  - Buy Research Chems  - Buy Legal Highs -  Buy Herbal Highs  - Drug Forum

SEO Services Big Idea SEO     Research Chemicals EU     Buy-Ethyl-Hexedrone

Buy Legal Highs UK 

Research Chemical Drug infomation site on Drugs
Picture